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Beth Stevens
Beth Stevens (b. ) is an assistant professor in the Department of Neurology at Harvard Medical School and the F. M. Kirby Neurobiology Center at Boston Children’s Hospital.〔 She has helped to identify the role of microglia in the “pruning” or removal of synaptic cells during brain development and has also determined that the impaired microglial function and abnormal activation of this pruning pathway could be responsible for diseases like autism, schizophrenia, and Alzheimer's.
In 2012, Stevens’ team published evidence that microglia 'eat' synapses, especially those that are weak and unused. The findings pinned down a new role for microglia in wiring the brain, indicating that adult neural circuitry is determined not only by the nerve cells but also by the brain’s immune cells, and helped to explain how the brain, which starts out with a surplus of neurons, trims some of the excess away. Neuron named the paper its most influential publication of 2012.〔(【引用サイトリンク】url=http://www.cell.com/neuron/twenty-five-years )〕
She continues to study the function of microglia in the healthy brain, most recently uncovering preliminary evidence that a certain protein serves as a ‘don’t eat me’ tag that protects synapses from being engulfed by microglia.〔(【引用サイトリンク】url=https://spectrumnews.org/news/profiles/beth-stevens-casting-immune-cells-as-brain-sculptors/ )〕 She received a MacArthur Fellowship in 2015.〔
== Education ==
Beth Stevens received a B.S. (1993) from Northeastern University, and a PhD in Neuroscience in 2003 from the University of Maryland, College Park. She completed her postdoctoral fellowship at the Stanford University School of Medicine in 2008.〔(【引用サイトリンク】title=Stevens Lab )〕
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